1268: The Benefit of Intravenous Ascorbic Acid, Hydrocortisone, and Thiamine in Sepsis and Septic Shock
نویسندگان
چکیده
منابع مشابه
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock
METHODS: In this retrospective before-after clinical study, we compared the outcome and clinical course of consecutive septic patients treated with intravenous vitamin C, hydrocortisone, and thiamine during a 7-month period (treatment group) with a control group treated in our ICU during the preceding 7 months. The primary outcome was hospital survival. A propensity score was generated to adjus...
متن کاملHydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
BACKGROUND The global burden of sepsis is estimated as 15 to 19 million cases annually, with a mortality rate approaching 60% in low-income countries. METHODS In this retrospective before-after clinical study, we compared the outcome and clinical course of consecutive septic patients treated with intravenous vitamin C, hydrocortisone, and thiamine during a 7-month period (treatment group) wit...
متن کاملThe effect of physiologic dose of intravenous hydrocortisone in patients with refractory septic shock: a randomized control trial
Objective: Septic shock is a response to infection and tissue hypoperfusion which does not respond to fluid therapy and eventually leads to organ dysfunction. Aggressive treatment of a broad-spectrum antimicrobial and supportive measures are the cornerstones of successful treatment. In addition to the main treatment, there are adjunctive therapies. Steroids are one of the treat...
متن کاملIntravenous immunoglobulin for treating sepsis, severe sepsis and septic shock.
BACKGROUND Mortality from sepsis and septic shock remains high. Results of trials on intravenous immunoglobulins (IVIG) as adjunctive therapy for sepsis have been conflicting. This is an update of a Cochrane review that was originally published in 1999 and updated in 2002 and 2010. OBJECTIVES To estimate the effects of IVIG as adjunctive therapy in patients with bacterial sepsis or septic sho...
متن کاملSepsis and Septic Shock
Septic shock (shock due to infection) and sepsis-associated multiple organ failure are the dominant cause of death in intensive care units of the industrialized world. As many as 800,000 cases of sepsis are admitted every year to American hospitals (comparable to the incidence of first myocardial infarctions), with half of those developing septic shock (1). Historically, the mortality associate...
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ژورنال
عنوان ژورنال: Critical Care Medicine
سال: 2020
ISSN: 0090-3493
DOI: 10.1097/01.ccm.0000730960.75375.8b